The Institute of Applied Biosciences (INAB) at the Center for Research and Technology Hellas (CERTH) aims to address the gap between research excellence and applications that meet end-user demands through close ties to interested stakeholders (SMEs, health sector, productive sector, social groups etc).
INAB has a leading position in the field of Agri-biotechnology aiming at understanding fundamental mechanisms underpinning a series of challenges mainly related to food safety and security, both global and local, especially concerning agri-genomics. Indeed, a major emphasis is given on genomics applications and molecular biotechnology for the production of food with improved quality; the development of new elite plant varieties, industrially relevant materials and genetically certified plant materials; and, finally, the establishment of microbial production systems of high added value products.
INAB is also conducting multidisciplinary Health Translational Research based on cutting-edge technologies with the main objectives of: dissecting cancer pathophysiology and identifying novel predictive biomarkers and novel therapeutic targets; understanding stem cell biology, especially of the hematopoietic and mesenchymal stem cells; advancing gene and cell therapy approaches for difficult to cure hematological diseases, both congenital and acquired, with a special focus on thalassemia; improving prevention, diagnosis and management of infections by the human papilloma virus; and, promoting pharmacological research, especially regarding biossimilars and generics.
INAB is very active in the field of Informatics for Big Biodata. Its competences start from big data management, analytics and interpretation with data stemming from biomolecular to streaming data, to telemonitoring, medication, and social media data. E-Health systems based on medical devices and ICT are built aiming in producing third generation telemonitoring systems enabling disease management of chronic patients, multi-morbid patients, as well as preventive monitoring of healthy individuals. Finally, in-silico modeling of the human organism beyond the cellular level in the cardiovascular system as well as in the mental/immuno systems is a major focus of INAB.