«Arkagathos Gouttas» Prize (Award), 26th Hellenic Ηematology Congress

26th Hellenic Ηematology Congress, 12-14 November 2015

Title

DISTINCT METHYLATION PATTERNS IN SUBGROUPS OF PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA REVEAL TP63 AS A NEW PLAYER IN CLINICAL AGGRESSIVENESS 

Recipients of the distinction

Stavroula Ntoufa, Nikos Papakonstantinou, Maria Tsagiopoulou, Theodoros Moisiadis, Antigoni Malousi, Despoina Papazoglou, Kostas Pasentsis, Fotis Psomopoulos, Evangelia Stalika, Mata Laidou, Nikolaos Maglaveras, Achilles Anagnostopoulos, Kostas Stamatopoulos

Short description

Chronic Lymphocytic Leukemia (CLL) is characterized by aberrant methylation patterns.  In this study we showed differential methylation profiles between cases belonging to stereotyped subset #6 and #8. The analysis revealed TP63 as a differentially express gene which acts as a prosurvival factor for CLL cells.

 

Contact

Stavroula Ntoufa
E-mail: sntoufa@certh.gr
Tel: (0030) 2310 498472