INTRODUCTION
The Institute of Applied Biosciences at the Centre for Research and Technology Hellas (INAB|CERTH) conducts research in the Life Sciences that extends from microbes to plants, animals and humans.
Our aim at INAB is to promote basic research, while providing solutions to important social needs related to health and well-being.
In this context, INAB conducts Biomedical research and deals with the development and evaluation of digital health interventions and personalized medicine, while also holding a leading position in Agri-biotechnology, utilizing modern high-performance methodologies, molecular biotechnology and 'breeding by design' approaches, with the aim of developing high quality and value products.
We work towards this direction with the basic principle of cooperation between scientists with different but complementary knowledge and skills. The main pillars of our activity are bioanalysis, data from the real world and the development of relevant applications.
INAB’s researchers play an important role in identifying, disseminating and supporting good research and educational practices, thus facilitating interaction between scientists, authorities and society. This, strengthens our cooperation with critical 'players' both nationally and internationally, giving them the opportunity to upgrade their services in critical areas such as health, agri-food, education and technological development.
At INAB, we believe that sustainability presupposes renewal based on both innovation and developments in technology and social needs. Thus, we will continue to be at the forefront of research on carefully selected areas of scientific, social and economic interest.
We rely on knowledge and cooperation, we innovate in the Life Sciences, we respond to social needs!
EXTERNAL ADVISORY BOARD
The External Advisory Board (EAB) supports the strategic development of the Institute of Applied Biosciences, enhancing the Institute’s continuous effort to achieve both scientific excellence and industry applicability.
The EAB was enacted on September, 2020. It consists of at 5 members, highly recognized and reputable in their respective fields.
For the 2020-2024 mission, the External Advisory Board consists of the following members:
- Constantinos Constantinidis | Owner and CEO, PELOPAC, Greece
- Marie-Christine Jaulent | Research Director, National Institute of Health and Medical Research (INSERM), France
- John Weinman | Professor of Psychology - School of Cancer & Pharmaceutical Sciences & Emeritus Professor at the Institute of Psychiatry, Psychology & Neuroscience in King’s College London. Co-Director of the KCL/KHP Centre for Adherence Research & Education, UK
- Phillip N. Tsichlis | MD, Chair, Department of Cancer Biology and Genetics, College of Medicine, The Ohio State University, US
- Richard Rosenquist Brandell | Professor of Clinical Genetics at the Department of Molecular Medicine and Surgery, Karolinska Institutet & Senior Physician in Clinical Genetics at Karolinska University Hospital, Sweden
UNITS
The Genomics Research Unit (GRU) uses genomic technologies to study the biology of humans and other organisms with the goal of achieving optimal health outcomes through the recognition of the interconnections between people, animals, plants, and their shared environment.
GRU research occurs across a spectrum: basic research to shed light on the structure and function of the genome; translational research to decipher the molecular bases of human diseases and healthy living; and, clinical research to establish how to use genomic information for advancing medical care.
GRU translates its research through its accredited Molecular Diagnostics Unit. The GRU employs over thirty research staff, including principal researchers, postdoctoral scientists, research assistants, postgraduate and honors students; is well equipped and funded by EU and national competitive grants as well as the industry.
GRU conducts a broad program of laboratory and clinical research to translate genomics into a greater understanding of diseases and develop better methods for the detection, prevention and treatment of heritable and genetic disorders.
The GRU bioinformatics branch focuses on computationally intensive approaches to analyze large-scale omics data from human to viruses and identifying genetic contributions to human disease.
GRU actively collaborates with many national and international institutions to advance research in areas as diverse as health, food tracing and environmental issues. Equipped with a wide range of state-of-the-art technology platforms, the facility aims to provide comprehensive, quality and reliable services for academic and private sector scientists alike. The Unit also offers expertise and know-how in molecular and cell biology, biostatistics and bioinformatics.
- GRU coordinates and takes part in projects based, in all or partly, on NGS technology
- GRU is open to academic and industrial research laboratories and collaborates with many national and foreign institutions
The Molecular Diagnostic Unit (MDU) specialises in providing fast, accurate diagnostic tests. Our ISO 15189-accredited and UKAS accredited unit employs the latest technology, including next-generation sequencing, to provide high-quality services to our national and international collaborators.
MDU also encompasses a Biobank [node of the Biobanking and BioMolecular resources Research Infrastructures (BBMRI)] and a Sample Monitoring System to optimise the management of patient samples.
The Unit is constantly researching and developing new molecular diagnostic methods which can be introduced into the clinical practice. This allows us to remain ahead of the field in diagnostic testing and clinical monitoring and to provide the highest quality of patient care. Our work is particularly centred on hematooncology and infectious diseases (HPV, SARS CoV-2).
In more detail, MDU is entrusted to provide our National Health System’s hospitals with a wide range of sensitive, specific, reliable and updated diagnostic tests. By using state-of-the-art molecular techniques, we routinely identify alterations in the sequence or the expression of key genes that are involved in the pathogenesis of human diseases and that could in turn be used in the diagnosis and/or prognosis of patients as well as in the monitoring of the response to therapy.
MDU is actively involved in the global efforts to standardise and improve molecular diagnostics testing, we work in partnership with international and national consortia dedicated to these objectives. Finally, our Unit remains fully committed to promoting laboratory training and mentoring for students, technicians and medical residents.
For further information on each of our diagnostic services please follow the links below.
- European Hematology Association Reference lab:
- TP53 gene analysis with Sanger sequencing and targeted NGS: http://www.ericll.org/structure-of-the-tp53-network/
- IGHV gene somatic hypermutation analysis: http://www.ericll.org/structure-of-the-ig-network/
- Identification of mutations in hematologic malignancy genes (panels) | targeted NGS - Coordinator of the Hellenic Network of Precision Medicine on Cancer: https://oncopmnet.gr/?page_id=608
- Identification of solid tumors gene mutations (panels) | targeted NGS - Coordinator of Hellenic Network of Precision Medicine on Cancer: https://oncopmnet.gr/?page_id=608
- Identification of genetic variants of inherited cardiovascular diseases (panels) | targeted NGS - Member ofGreek National Network of Precision Medicine in Cardiology and the Prevention of Sudden Death in the Young: https://icardiacnet.gr/en/421-2/
- Molecular detection of HPV virus in the population of Greece (11 thousand women) in the context of a study evaluating the methodology of self-sampling of cervical material - "Greco self" screening program for cervical cancer.
- Repertory studies of B cell receptor (BcR) gene rearrangements in international clinical trials
- Repertoire studies of T cell receptor (TcR) gene rearrangements in international clinical trials
- Molecular detection of SARS-CoV-2 virus in collaboration with the National Public Health Organisation (EODY)
- Analysis of the SARS-CoV-2 genome for the detection of virus variants - Reference Laboratory for Northern Greece
CERTIFICATIONS
INAB is certified according to ISO/IEC 27001:2013 for its Information Security Management System, which has designed and maintained since 2018. Achieving this important goal gives INAB a distinction among all Hellenic Research Centers and Academic Institutions.
INAB is certified according to ISO 22301:2019 for its Business Continuity Management System.
INΑB has installed and implements a Quality Management System according to the ELOT EN ISO/IEC 15189:2012 Standard, the relevant documents of ESYD, as well as any other specifications related to the activities of the Laboratories. ΙΝΑΒ is committed to complying with the requirements of the above Standard and continuously improving its efficiency.
The laboratories participate in external quality control schemes and are constantly updating their certificates as well as enriching their fields of accreditation with new ones. You can see here, the Institute's "Table of Participation in interlaboratory schemes".
The vision of ΙΝΑΒ is to provide reliable results of genetic and molecular tests and in general to achieve and maintain the highest possible level of quality in all services it provides.
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GDPR
Information on Personal Data Protection in accordance with Regulation (EU) 2016/679
Since 25/5/2018 the General Data Protection Regulation (EU) 2016/679, also known as GDPR, is being implemented, which strengthens the framework for the protection of data subjects with regard to the processing of personal data in the European Union. INAB | CERTH with respect to personal data, complies with the GDPR in the context of its activity and scope and takes the respective technical and organizational measures for the effective protection of personal data, in accordance with the GDPR.
The Institute of Applied Βιο-Sciences of the Centre for Research and Technology Hellas (INAB | CERTH) aims to bridge the gap between excellence research in the field of life sciences and applications that meet the needs of end users. In this endeavor, with full respect for human value and privacy, the Institute has developed a complete Personal Data Protection Program, to fully ensure the protection of patients and study participants. Researchers and employees act in accordance with applicable Greek and European law, as well as international rules resulting from agreements or decisions of international organizations in which our country participates.
Active and dynamic participation of all INEB employees in the Personal Data Protection Program ensures that program performance audits are regularly audited and that the level of protection of personal data in the possession of the institute. To achieve these goals INAB has designed and is maintaining an Information Security Management System (ISMS). INAB is certified acording to ISO 27001:2013 for its ISMS.
In this context, the processing that takes place concerns the personal data you provide to INAB | CERTH when you visit our official web sites, when using our services or interact with us, for example by sending a contact form.
Such personal data is:
Identification data (e.g., User ID, Full Name, Father’s & Mother’s Name, Photo, Identity or Passport Number, etc.)
Communication data (e.g. postal address, phones numbers, e-mail address, etc.)
Demographic data (e.g., Nationality, Citizenship, Religion, Date of Birth, Place of Birth, Country of Birth etc.)
Health Data (e.g. Medical opinions, Medical Certificates, Medical Samples etc.)
Curriculum Vitae (CV)
consent to the processing of your personal data for one or more specific purposes
for the performance of a contract
for compliance with our legal obligations
in order to protect your or another natural person’s vital interests
for the performance of a task carried out in the public interest
for the purposes of our legitimate interests
INAB | CERTH might process your personal data for the following purposes by legal basis:
Consent to the processing of your personal data for one or more specific purposes
To identify and communicate with you
For the performance of a contract
For communication during pre-contract or contract performance
For compliance with our legal obligations
To fulfill our obligations, imposed by current legislation, on our students, our staff and our external collaborators.
To fulfill our obligations under applicable law on disclosure to Public Authorities.
In order to protect your or another natural person’s vital interests
• for medical examinations / tests
For the performance of a task carried out in the public interest
To understand the pathogenicity of diseases and to develop and validate innovative methodologies, products and services of medical interest
For the purposes of our legitimate interests, such as:
• To develop and improve our services through your activities and interests.
• Complaints management
• For the protection and security of our IT systems
• For the protection and safety of our facilities
• To manage risks from breaching the obligations arising from sponsorship contracts.
The personal data collected will be limited to the minimum necessary and will remain in our possession for the purpose of the examination / analysis for which it is intended, as well as for 6 months thereafter, in order to satisfy any of your requests relating to validating the analysis of results.
Once you have given us your consent, your clinical sample, along with the anonymized information that accompanies it, may be used in research aimed at improving patient health, as well as their life expectancy and quality of life.
In all cases where the processing is based on consent, INEB | CERTH follows the procedures provided by law.
INAB | CERTH may be required or entitled to disclose your personal data to a number of third parties such as:
Public authorities
Independent authorities
Research Institutes, Universities and Hospitals (if you are involved in research, with your consent)
provided that privacy and confidentiality is always respected.
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• Are processed and treated lawfully and fairly in a transparent manner with respect to the data subject
• Are collected solely for specific and legitimate purposes
• Are adequate, they are related to the purpose for which we collect them and are limited to what is necessary
• Are accurate and up-to-date
• Are maintained exclusively within the specified timeframe and no longer
• Are processed in a way as to ensure the necessary security of personal data
You may at any time be informed by us of and access to your personal data we hold.
• Correction
You have the right to contact us to correct the data that is inaccurate or incomplete.
• Erasure
If we are not obliged by law to maintain the data we hold and relate to you, you can ask for your personal data to be deleted.
• Data Portability
You can ask us to forward your data to another authority.
• The right to oppose and limit processing
In case you disagree with the way we process your personal data, you can request the interruption or limitation of the processing
• The right to withdraw consent
You have the right to withdraw your consent to process your data at any time.
INAB | CERTH will make every effort to respond to your request without delay and in any case within one month of receiving it. This period is extended for a further two months if it is necessary taking into account the complexity of the request and the number of requests. INAB | CERTH will inform you of this extension within one month of receipt of the request and of the reasons for the delay. If you have submitted the request by electronic means, the update is provided, if possible, by electronic means, unless you request otherwise.
In case INAB | CERTH satisfies your request (a) to limit the processing of your data; or (b) to terminate the processing of your data; or (c) to delete your data from the University’s records and if they are necessary for the preparation or continuation and performance of a contract, then either the termination by you of the relevant agreement or the inability to process your request is automatically implied.
INAB | CERTH is in any case entitled to refuse the satisfaction of your request to restrict the processing or deletion of your personal data if such processing is necessary for the foundation, exercise or support of its legitimate rights or the fulfillment of its obligations.
The above services are provided free of charge. However, if your claims are manifestly unfounded, excessive or recurrent, INAB | CERTH may either impose a reasonable end, inform you or refuse to respond to them.
To exercise your rights click here
Institute of Applied Biosciences
Centre for Research and Technology Hellas
6th Km. Charilaou – Thermi Road
P.O. BOX 60361 GR – 57001
Thessaloniki
Hellas
and we will respond to you as soon as possible and not later than one month.
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Data Request Form
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